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Injectable peptides for anti-aging?

January 10, 2023

Injectable peptides for anti-aging?

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--First, lets break down what a peptide is--

Peptides are chains of amino acids. Amino acids are the building blocks of proteins in the body. Proteins are needed for a multitude of reasons. In particular, to help build and repair damaged cells.


--Why are you telling me this?--

As you reach age 20, your body begins to lose something called collagen. Collagen is made up of the following amino acids: glycine, proline, and hydroxyproline. What are amino acids made up from? Peptides. 


 By age 40, your body will lose approximately 1% per year. This process is sped up by menopause. The loss of collagen attributes to the formation of wrinkles and fine lines, loss of skin elasticity.


--But, I read somewhere that using collagen to reverse signs of aging is a myth?--

Absolutely it is. The collagen molecules are far too large to be effective. However, breaking down collagen to amino acids and then further breaking down amino acids into...you guessed it: Peptides. Making this a usable form for your body to help repair damage because it is much, much smaller.


--Wrapping up and fast facts--

  1. Many peptides are obtained from plant derivatives, you can read more about that here
  2. According to Jeong et al, improvement was able to be seen in as little as two weeks (You can view the article here). 
  3. Another article states that the results of the study demonstrate that the collagen-like peptide acts deeply and intensely on wrinkles and was effective in approximately 75-80% of the participants. 

In summary, peptide therapy is in large demand due to the proven anti-aging properties by countless studies.

References:

Bauza, E., Oberto, G., Berghi, A., Dal, C. F., & Domloge, N. (2004). Collagen-like peptide exhibits a remarkable antiwrinkle effect on the skin when topically applied: in vivo study. International journal of tissue reactions, 26(3-4), 105–111. 


 Lee, A. C., Harris, J. L., Khanna, K. K., & Hong, J. H. (2019). A Comprehensive Review on Current Advances in Peptide Drug Development and Design. International journal of molecular sciences, 20(10), 2383. https://doi.org/10.3390/ijms20102383 


Jeong, S., Yoon, S., Kim, S., Jung, J., Kor, M., Shin, K., Lim, C., Han, H. S., Lee, H., Park, K. Y., Kim, J., Chung, H. J., & Kim, H. J. (2019). Anti-Wrinkle Benefits of Peptides Complex Stimulating Skin Basement Membrane Proteins Expression. International journal of molecular sciences, 21(1), 73. https://doi.org/10.3390/ijms21010073 

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